August 19, 2008
The genetics of vertebrate myogenesis.
Publication Date: 2008 Aug PMID: 18636072
Authors: Bryson-Richardson, R. J. - Currie, P. D.
Journal: Nat Rev Genet
The molecular, genetic and cellular bases for skeletal muscle growth and regeneration have been recently documented in a number of vertebrate species. These studies highlight the role of transient subcompartments of the early somite as a source of distinct waves of myogenic precursors. Individual myogenic progenitor populations undergo a complex series of cell rearrangements and specification events in different regions of the body, all of which are controlled by distinct gene regulatory networks. Collectively, these studies have opened a window into the morphogenetic and molecular bases of the different phases of vertebrate myogenesis, from embryo to adult.
MeSH Categories: Animals, Embryo, Mammalian, Embryo, Nonmammalian, Head/embryology, Heart/embryology/physiology, Humans, Models, Biological, Muscle Development/*genetics, Muscles/*embryology, Organ Specificity/genetics, RNA, Messenger/metabolism/physiology, Vertebrates/*genetics
post to: CiteULike
Authors: Bryson-Richardson, R. J. - Currie, P. D.
Journal: Nat Rev Genet
The molecular, genetic and cellular bases for skeletal muscle growth and regeneration have been recently documented in a number of vertebrate species. These studies highlight the role of transient subcompartments of the early somite as a source of distinct waves of myogenic precursors. Individual myogenic progenitor populations undergo a complex series of cell rearrangements and specification events in different regions of the body, all of which are controlled by distinct gene regulatory networks. Collectively, these studies have opened a window into the morphogenetic and molecular bases of the different phases of vertebrate myogenesis, from embryo to adult.
MeSH Categories: Animals, Embryo, Mammalian, Embryo, Nonmammalian, Head/embryology, Heart/embryology/physiology, Humans, Models, Biological, Muscle Development/*genetics, Muscles/*embryology, Organ Specificity/genetics, RNA, Messenger/metabolism/physiology, Vertebrates/*genetics
post to: CiteULike
Filed under Genetics Publications by Nature Reviews Genetics
